The England Under 21 side returned to the National Stadium on 5 September 2008. Stuart Pearce's side played Portugal's Under-21 team in the UEFA Under-21 European Championship Group 3 match. A 20,000 crowd witnessed a James Milner penalty and a Gabby Agbonlahor goal as England ran out two-nil victors in a side that also included Joe Hart in goal, Tom Huddlestone and Adam Johnson.

Before the year was out, Stuart Pearce took his Under-21 side back to the National Stadium. They were runners-up in the previous UEFA Under-21 European Championship Finals. Again, Portugal were the visitors, and again, England were victors, with a single Danny Rose goal in front of a 33,833 crowd. The team also included Kieran Gibbs, Micah Richards, Chris Smalling, Ryan Bertrand, Tom Cleverley, Fabian Delph and Andy Carroll.

Season 2012-13
World Cup Preliminary matches
912	11 September 2012 - England 1 Ukraine 1 [0-1] (68,102)	Lampard (pen) Konoplyanka	Draw
		Steven Gerrard
	The second England player to be sent off at Wembley Stadium, the first at the new National Stadium, the thirtieth match at the new stadium.
913	12 October 2012 - England 5 San Marino 0 [2-0] (85,654)	Rooney (2 (1 pen)), Welbeck (2), Oxlade-Chamberlain	Win
Friendly matches
916	6 February 2013 - England 2 Brazil 1 [1-0] (87,453)	Rooney, Lampard Fred	Win
919	29 May 2013 - England 1 Republic of Ireland 1 [1-1] (80,126)	Lampard Long	Draw
P 4 W 2 D 2 L 0 F 9: A 3 ave att: 80,333

Before the year was out, Mark Sampson completed his first year as the Women's team manager by entertaining the German Women team at the National Stadium in a friendly match. A record crowd for a women's game in England, 45,619, watched the German's win 3-0.

Season 2015-16
946	8 September 2015 - England 2 Switzerland 0 [0-0] (75,751)	Kane, Rooney (pen)	Win
		Wayne Rooney scores in five consecutive matches at the National Stadium
947	9 October 2015 - England 2 Estonia 0 [1-0] (75,427)	Walcott, Sterling	Win
Friendly matches
950	17 November 2015 - England 2 France 0 [1-0] (71,223)	Alli, Rooney	Win
		Dele Alli is the thirtieth different goalscorer at the National Stadium
952	29 March 2016 - England 1 Netherlands 2 [1-0] (82,831)	Vardy Janssen (pen), Narsingh	Lost
955	2 June 2016 - England 1 Portugal 0 [0-0] (82,503)	Smalling	Win
		Bruno Alves
		England's 50th match at the new National Stadium
record: P 5 W 4 D 0 L 1 F 8: A 2 ave att: 77,547		Hodgson's record: P 22 W 17 D 2 L 3 F 48: A 12 ave att: 75,838

Phil Neville took his Women's team to the National Stadium in another friendly match with the German Women team. Another record crowd for the women's game in England when 77,768 watched the German's win again, by two goals to one.